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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHRS11 All Species: 26.97
Human Site: Y171 Identified Species: 53.94
UniProt: Q6UWP2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UWP2 NP_077284.2 260 28308 Y171 H F Y S A T K Y A V T A L T E
Chimpanzee Pan troglodytes XP_511425 274 29730 Y185 H F Y S A T K Y A V T A L T E
Rhesus Macaque Macaca mulatta XP_001111397 255 27833 Y166 H F Y S A T K Y A V T A L T E
Dog Lupus familis XP_548249 274 29660 Y185 H F Y S A T K Y A V T A L T E
Cat Felis silvestris
Mouse Mus musculus Q3U0B3 260 28256 Y171 H F Y S A T K Y A V T A L T E
Rat Rattus norvegicus Q5M875 300 33476 F195 S K F A A V G F H R A L T A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q71R50 255 27708 Y166 H F Y S A T K Y A V T A L T E
Frog Xenopus laevis NP_001088432 181 19907 L97 T K Y A V T A L T E G I R Q E
Zebra Danio Brachydanio rerio NP_001093518 258 28208 Y169 H F Y C A T K Y A V T A M T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780227 255 28419 H166 H F Y A G T K H M V K A L T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P33207 319 33530 I234 A A A K G G V I S F S K T A A
Baker's Yeast Sacchar. cerevisiae Q05016 267 29140 F173 S I Y C A S K F A V G A F T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.2 97.3 89 N.A. 92.6 21.6 N.A. N.A. 78.8 54.2 73 N.A. N.A. N.A. N.A. 46.9
Protein Similarity: 100 82.1 97.3 91.6 N.A. 96.1 39 N.A. N.A. 89.2 61.9 86.1 N.A. N.A. N.A. N.A. 65.7
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 100 20 86.6 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. N.A. 100 26.6 93.3 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 21.9 30.3 N.A.
Protein Similarity: N.A. N.A. N.A. 39.5 49.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 25 75 0 9 0 67 0 9 75 0 17 9 % A
% Cys: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 84 % E
% Phe: 0 67 9 0 0 0 0 17 0 9 0 0 9 0 0 % F
% Gly: 0 0 0 0 17 9 9 0 0 0 17 0 0 0 0 % G
% His: 67 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 9 0 0 0 9 0 0 0 % I
% Lys: 0 17 0 9 0 0 75 0 0 0 9 9 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 9 0 0 0 9 59 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % R
% Ser: 17 0 0 50 0 9 0 0 9 0 9 0 0 0 0 % S
% Thr: 9 0 0 0 0 75 0 0 9 0 59 0 17 75 0 % T
% Val: 0 0 0 0 9 9 9 0 0 75 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 84 0 0 0 0 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _